Increased liver stiffness

There is 1 paper on increased liver stiffness in aging research: 1 observational study in people.

Biomarker

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“WHtR and WC demonstrated greater discrimination than BMI for hepatic steatosis (WAUC 0.82-0.83 vs 0.81) and increased liver stiffness (WAUC 0.76 vs 0.74)”
Waist-to-Height Ratio Outperforms BMI in Identifying Hepatic Steatosis and Fibrosis in U.S. AdultsADA Scientific Sessions 2026 abstract2026doi:10.2337/db26-2600-p
  • Humans1

Associations

1

Waist-to-height ratio

upin humans1

1 study
  1. Waist-to-height ratio is associated with increased liver stiffness in humans (elevated WHtR at high-risk threshold) (PR 3.92; 95% CI 2.36-6.51).

    “elevated WHtR was associated with markedly higher prevalence of hepatic steatosis (PR 10.45; 95% CI 6.74-16.22) and increased liver stiffness (PR 3.92; 95% CI 2.36-6.51)”

    Humanselevated WHtR at high-risk thresholdlivern = 3,905

    Waist-to-Height Ratio Outperforms BMI in Identifying Hepatic Steatosis and Fibrosis in U.S. Adults

    ADA Scientific Sessions 2026 abstract

  2. Waist-to-height ratio predicts increased liver stiffness in humans (compared with body mass index) (WAUC 0.76 vs 0.74 for BMI).

    “WHtR and WC demonstrated greater discrimination than BMI for hepatic steatosis (WAUC 0.82-0.83 vs 0.81) and increased liver stiffness (WAUC 0.76 vs 0.74)”

    Humanscompared with body mass indexlivern = 3,905

    Waist-to-Height Ratio Outperforms BMI in Identifying Hepatic Steatosis and Fibrosis in U.S. Adults

    ADA Scientific Sessions 2026 abstract

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