Incomplete retinal pigment epithelial and outer retinal atrophy

Biomarker

1 paper studies it2 findings

See all 1

  • Humans1

Effects

1

Geographic atrophy

no changein humans1

1 study
  1. Incomplete retinal pigment epithelial and outer retinal atrophy has no effect on geographic atrophy in humans (adjusted P = 0.520).

    “only the specific nGA features (adjusted P < 0.001), and not iRORA (adjusted P = 0.520), were associated with an increased rate of GA development when both features were included in the same multivariable model”

    Humansin multivariable model with nGAretinaup to 36 monthsn = 140

    Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy: Longitudinal Evaluation in Age-Related Macular Degeneration

    Ophthalmology

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Associations

1

Geographic atrophy

upin humans1HR 12.1

1 study
  1. Incomplete retinal pigment epithelial and outer retinal atrophy raises the risk of geographic atrophy in humans (adjusted HR 12.1, P = 0.021).

    “prevalent or incident iRORA was associated with an increased rate of GA development (adjusted hazard ratio [HR], 12.1; P = 0.021)”

    Humansbilateral large drusen without late AMD at baselineretinaup to 36 monthsn = 140

    Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy: Longitudinal Evaluation in Age-Related Macular Degeneration

    Ophthalmology

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