Foveal pit volume

There are 2 papers on foveal pit volume in aging research: 2 observational studies in people. The newest story, Nov 3, 2026: “Shape of eye’s central pit is strongly linked to genetics”.

Biomarker

2 papers study it2 findings

1 new paper in 30 daysSee all 2

“Foveal pit volume is associated with future risk of age-related macular degeneration (AMD) (hazard ratio 1.09, p = 0.026)”
Genetic insights into foveal morphology and its associations with pigmentation and age-related macular degenerationCommunications biology2026doi:10.1038/s42003-026-11248-y
  • Humans2

Associations

1

Age-related macular degeneration

upin humans1HR 1.09

1 study
  1. Foveal pit volume is associated with age-related macular degeneration in humans (HR 1.09).

    “Foveal pit volume is associated with future risk of age-related macular degeneration (AMD) (hazard ratio 1.09, p = 0.026)”

    Humansfovea

    Shape of eye’s central pit is strongly linked to genetics

    Communications biology

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Communications Biology

Shape of eye’s central pit is strongly linked to genetics

In 39,521 UK Biobank participants, genetic differences accounted for an estimated 29% to 43% of variation across six measures of the retina’s central pit.In 39,521 UK Biobank participants, genetic differences accounted for an estimated 29% to 43% of variation across six measures of the retina’s central pit.

Genetic association · 39,521 peopleBiomarkers