What does the research say about FLAIR-DIR-derived contrast?

FLAIR-DIR-derived contrast

There is 1 paper on FLAIR-DIR-derived contrast in aging research: 1 observational study in people.

1 paper studies it2 findings

“Voxel-wise analyses revealed that better odor identification was associated with higher FD in the hippocampus/parahippocampal and insula”

Mild cognitive impairment

downin humans1

1 study

Mild cognitive impairment is linked with lower FLAIR-DIR-derived contrast in humans (compared with healthy controls).
“Compared with HC, MCI showed significantly lower FD across olfactory-limbic gray-matter regions and white-matter pathways-including hippocampus, amygdala, orbitofrontal cortex, thalamus, and corpus callosum”
Humanscompared with healthy controlsbrainn = 33
A DERIVED RELAXATION CONTRAST FROM SYNTHETIC MRI FOR DETECTING NETWORK MICROSTRUCTURAL VULNERABILITY
bioRxiv : the preprint server for biologyApr 12, 2026Preprint

Odor identification score

upin humans1

1 study

FLAIR-DIR-derived contrast is associated with odor identification score in humans.
“Voxel-wise analyses revealed that better odor identification was associated with higher FD in the hippocampus/parahippocampal and insula”
Humanshippocampusn = 33
A DERIVED RELAXATION CONTRAST FROM SYNTHETIC MRI FOR DETECTING NETWORK MICROSTRUCTURAL VULNERABILITY
bioRxiv : the preprint server for biologyApr 12, 2026Preprint

1 paper in 12 months

bioRxivApr 17

Preprint: case-control study of 33 peopleBiomarkers