Dopamine clearance timescales
Biomarker1 paper1 finding
- Humans1
Associations
1Cognitive function
downin humans1
1 study
Cognitive function
downin humans1
Dopamine clearance timescales are associated with cognitive function in humans.
“Critically, low performers exhibit elevated clearance in adults with marked structural degradation, and only within sliding age windows centred between 56 and 76 years.”
Humansin adults with marked structural degradation, within sliding age windows centred between 56 and 76 yearsbrainn = 3,650
Dopamine clearance–cognition link varies by age and structure · bioRxiv · 5 Oct 2026 · Preprint
Latest
1bioRxivHumansPreprint
Dopamine clearance–cognition link varies by age and structure
In 3,650 adults, elevated modeled dopamine clearance was linked to poorer cognition only with marked structural degradation and within sliding age…In 3,650 adults, elevated modeled dopamine clearance was linked to poorer cognition only with marked structural degradation and within sliding age windows centered between 56 and 76 years.