Research Square
Daily difficulties linked to mortality within cognitive stages
Three-year mortality with none versus all four difficulties was 21.0% versus 41.0% at cognitive stage 1 and 26.8% versus 59.0% at stage 3.Three-year mortality with none versus all four difficulties was 21.0% versus 41.0% at cognitive stage 1 and 26.8% versus 59.0% at stage 3.

Preprint: cohort · 194,728 peoplePopulations
Who was studied194,728 older adults with cognitive impairment, median 2.43 years
What changedWithin each cognitive stage, three-year mortality roughly doubled among people with all four everyday difficulties versus none
The catchComorbidity, nutrition, and medication data were unavailable, leaving likely confounding