Decreased CRABP2 expression

1. Decreased CRABP2 expression induces cellular senescence in human cells (old female donors).

   “in old males decreased expression of CRABP2 leads to cell proliferation, whereas in old females it leads to cellular senescence.”

   Cellsold female donorstissue-engineered tendonfemales

   Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females

   Scientific reports·Oct 31, 2017

More on Cellular senescence

1. Decreased CRABP2 expression induces cell proliferation in human cells (old male donors).

   “in old males decreased expression of CRABP2 leads to cell proliferation”

   Cellsold male donorstissue-engineered tendonmales

   Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females

   Scientific reports·Oct 31, 2017