What does the research say about Day-to-night urea excretion ratio?

Day-to-night urea excretion ratio

There is 1 paper on day-to-night urea excretion ratio in aging research: 1 observational study in people. The newest story, Oct 30, 2026: “Adults had higher nighttime output of a protein breakdown marker”.

Biomarker

1 paper studies it2 findings

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“Across the cohort, a predominant nocturnal pattern of urinary urea excretion was observed, with a mean Day/Night ratio below 1.”

Circadian Modulation of Protein Catabolism: Insight from a Population StudyNutrients2026doi:10.3390/nu18101594

Humans1

Associations

Age

upin humans1

1 study

age is associated with day-to-night urea excretion ratio in women.
“whereas older women (>65 years) displayed a significantly more pronounced nocturnal predominance.”
Humansin womenfemales
Adults had higher nighttime output of a protein breakdown marker
NutrientsMay 17, 2026

Circadian clock

downin humans1

1 study

Circadian clock is associated with day-to-night urea excretion ratio in humans across the cohort (mean Day/Night ratio below 1).
“Across the cohort, a predominant nocturnal pattern of urinary urea excretion was observed, with a mean Day/Night ratio below 1.”
Humansacross the cohortn = 859
Adults had higher nighttime output of a protein breakdown marker
NutrientsMay 17, 2026

Latest

1 paper in 12 months

NutrientsMay 27

Adults had higher nighttime output of a protein breakdown marker

Among 859 adults, the mean daytime-to-nighttime ratio of hourly urinary urea output was below 1, indicating greater nighttime output.Among 859 adults, the mean daytime-to-nighttime ratio of hourly urinary urea output was below 1, indicating greater nighttime output.

Cross-sectional · 859 peopleMechanisms

Paper

Day-to-night urea excretion ratio

Associations

Latest

Adults had higher nighttime output of a protein breakdown marker

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