CYP2D6-specific anticholinergic burden score

There is 1 paper on CYP2D6-specific anticholinergic burden score in aging research: 1 observational study in people.

Biomarker

1 paper studies it1 finding

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“ABS2D6 showed a significant association with falls in logistic regression analysis of OR 1.57 [95%CI 1.09-2.26].”
Fall-risk in genetic variable cytochrome P450 enzymes and exposure to anticholinergic drugs - a pilot-analysis from the ADRED-studyPharmacogenomics2026doi:10.1080/14622416.2026.2754846
  • Humans1

Associations

1

Falls

upin humans1OR 1.57

1 study
  1. CYP2D6-specific anticholinergic burden score is associated with falls in humans (Use of ≥three drugs) (OR 1.57, 95% CI 1.09–2.26).

    “ABS2D6 showed a significant association with falls in logistic regression analysis of OR 1.57 [95%CI 1.09-2.26].”

    HumansUse of ≥three drugsn = 659

    Fall-risk in genetic variable cytochrome P450 enzymes and exposure to anticholinergic drugs - a pilot-analysis from the ADRED-study

    Pharmacogenomics

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