Combined amyloid and tau status

Combined amyloid and tau status is associated with practice-related cognitive benefit in humans (A+T+ compared with A-T- participants).

“participants who were A+T+ did not appear to benefit from practice as much as the A-T- participants did.”

HumansA+T+ compared with A-T- participantsn = 397

Amyloid and tau may moderate practice effects in semantic and episodic memory in a cognitively unimpaired at-risk sample

Brain communications·Oct 9, 2025