ESC Congress 2026 Abstract
Protein loss made irregular rhythms harder to trigger in mice
Aging mice lacking the protein in heart muscle cells had reduced structural changes in the heart’s upper chambers and lower susceptibility to an experimentally triggered…Aging mice lacking the protein in heart muscle cells had reduced structural changes in the heart’s upper chambers and lower susceptibility to an experimentally triggered irregular heartbeat.
Mouse studyMechanisms
Who was studiedAging mice
What changedSusceptibility to experimentally triggered atrial fibrillation was lower in aging mice lacking Reg3γ in heart muscle cells
The catchSpontaneous atrial fibrillation was not measured; rhythms were triggered by programmed intracardiac stimulation