AHA Scientific Sessions 2026 Abstract
Gene variant linked to heart changes without heart failure
Compared with noncarriers, people with one copy had 2.09 times the odds of reduced heart-pumping function; those with two copies had 11.03 times the odds.Compared with noncarriers, people with one copy had 2.09 times the odds of reduced heart-pumping function; those with two copies had 11.03 times the odds.
Genetic association · 14,508 peopleBiomarkers
Who was studied14,508 African-ancestry participants without heart failure
What changedPeople with two copies had 11.03 times the odds of reduced heart-pumping function compared with noncarriers
The catchOther genetic differences between carriers and noncarriers could contribute to the heart-function association