Cd74 and MHC II gene expression

atherosclerosis and aging is associated with Cd74 and MHC II gene expression in mice.

“Cd74 and MHCII genes such as H2-Aa, H2-Ab1, H2-Eb1 , and H2-DMb1 are consistently upregulated”

Animalsatherosclerotic plaques, aging aorta and aging bone marrowmonocytes and macrophages from plaques, aorta and bone marrow

Increased expression of Cd74 and MHC II genes by aortic macrophages links atherosclerosis with aging in mice

bioRxiv (Cold Spring Harbor Laboratory)·Jul 21, 2026Preprint