Brain volume composite score

Biomarker

1 paper6 findings

  • Humans1

Effects

1

Cognitive function

mediatesin humans2

2 studies
  1. Brain volume composite score mediates cognitive function in humans.

    “brain volume partially mediated the relationship between sleep and cognition”

    Humansn = 467

    Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

    AAIC 2025 abstractDec 24, 2025

  2. Brain volume composite score mediates cognitive function in humans.

    “brain volume partially mediated the relationship between sleep and cognition”

    Humansadjusted for age, gender, and estimated intracranial volumebrainn = 467

    Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

    AAIC 2025 abstractDec 23, 2025

Associations

3

Cognitive function

upin humans2

2 studies
  1. Brain volume composite score is associated with cognitive function in humans (r = 0.15).

    “associations between brain volume composite scores and both sleep ( r = 0.18) and cognition ( r = 0.15) scores from the significant PLSC component”

    Humansn = 467

    Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

    AAIC 2025 abstractDec 24, 2025

  2. Brain volume composite score is associated with cognitive function in humans (r = 0.15).

    “brain volume composite scores and both sleep ( r = 0.18) and cognition ( r = 0.15) scores from the significant PLSC component.”

    Humanscommunity-dwellingbrainn = 467

    Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

    AAIC 2025 abstractDec 23, 2025

Sleep score

upin humans1

1 study
  1. Brain volume composite score is associated with sleep score in humans (r = 0.18).

    “Correlation analyses revealed significant associations between brain volume composite scores and both sleep ( r = 0.18) and cognition ( r = 0.15) scores”

    Humansn = 467

    Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

    AAIC 2025 abstractDec 24, 2025

More on Sleep score

Sleep regularity

upin humans1

1 study
  1. Brain volume composite score is associated with sleep regularity in humans (r = 0.18).

    “associations between brain volume composite scores and both sleep ( r = 0.18) and cognition ( r = 0.15) scores”

    Humanscommunity-dwellingbrainn = 467

    Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

    AAIC 2025 abstractDec 23, 2025

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