Age-related DNA methylation trend switch points

Age is associated with age-related DNA methylation trend switch points in humans (5175 CpG switch points mapped to 2813 genes in three waves; 80% identical in men and women).

“The 5175 switch points were limited to 2813 genes in three waves, 80% of which were identical in men and women.”

Humansmen and womensn = 2,143

Epigenetic aging waves: Artificial intelligence detects clustering of switch points in DNA methylation rate in defined sex-dependent age periods

bioRxiv (Cold Spring Harbor Laboratory)·Oct 5, 2022Preprint