Phase 4Completed
Randomized, Controlled Study to Investigate the 12-month Efficacy and Safety of Resveratrol Vitamin Supplements in Patients With Non-proliferative Diabetic Retinopathy Without Center Involved Diabetic Macular Edema (REVOLUTION Study)
- Sponsor
- University of Athens (Academic or other)
- Enrolment
- 100 enrolled
- Conditions
- Diabetic Retinopathy; Non Proliferative Diabetic Retinopathy; Prospective Study
- Interventions
- Resveratrol-Containing Vitamin Supplement
- Ages
- adults, older adults
- Registry
- NCT07868458
Full record on ClinicalTrials.gov
From the registry
This randomized, controlled study aims to investigate the efficacy and safety of resveratrol-containing vitamin supplements in patients with non-proliferative diabetic retinopathy (NPDR) without center-involved diabetic macular edema (DME). Patients with diabetes mellitus and NPDR attending the Second Department of Ophthalmology will be enrolled and randomly assigned to a supplementation or control group. During the 12-month follow-up period, the study will evaluate the potential effects of resveratrol supplementation on diabetic retinopathy, including changes in disease severity and progression, while also monitoring its safety and tolerability.
Primary outcomes
- Patients with improvement in diabetic retinopathy severity
History
Registered
Started
Primary completion