No phaseCompletedAge-related condition
CO₂ Laser With or Without Platelet-Rich Plasma for Genitourinary Syndrome of Menopause
Fractional CO₂ Laser Versus Combined CO₂ Laser and Platelet-Rich Plasma for the Management of Genitourinary Syndrome of Menopause: A Prospective Study.
- Sponsor
- National and Kapodistrian University of Athens (Academic or other)
- Enrolment
- 40 enrolled
- Conditions
- Genitourinary Syndrome of Menopause (GSM)
- Interventions
- Fractional CO₂ Laser; Autologous Platelet-Rich Plasma (PRP)
- Ages
- adults, older adults
- Registry
- NCT07863739
Full record on ClinicalTrials.gov
From the registry
This study evaluated whether adding platelet-rich plasma (PRP) to fractional CO₂ laser treatment provides additional benefit for postmenopausal women with genitourinary syndrome of menopause (GSM). Participants received either fractional CO₂ laser treatment alone or fractional CO₂ laser combined with PRP injections. Both groups received three treatment sessions at 4-6-week intervals. The main outcome was the change in vaginal dryness after treatment. Other outcomes included vaginal symptoms, sexual function, quality of life, and measures of vaginal health. The study also evaluated the safety and tolerability of both treatments.
Primary outcomes
- Change in Vaginal Dryness Severity
History
Last registry update
Registered
Primary completion
Started