No phaseNot yet recruiting
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy: a Randomized Controlled Trial
Treatment of Erectile Dysfunction After Radical Prostatectomy With Platelet-Rich Plasma Injections: a Randomized Controlled Trial
- Sponsor
- Herlev and Gentofte Hospital (Academic or other)
- Enrolment
- 100 planned
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy; Erectile Dysfunction
- Interventions
- Autologous Platelet Rich Plasma; saline solution (placebo)
- Ages
- adults, older adults
- Registry
- NCT07863388
Full record on ClinicalTrials.gov
From the registry
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate cancer. Participants will be randomly assigned to receive either two PRP injections or two saline (placebo) injections into the penis, administered one month apart in a double-blind fashion. Erectile function will be assessed using the International Index of Erectile Function (IIEF) questionnaire at baseline and at 1, 3, 6, and 12 months after the last injection. The primary objective is to determine whether PRP improves the erectile function domain of the IIEF more than saline at one month after the last injection
Primary outcomes
- Change in IIEF-EF score from baseline to 1 month after the final treatment session
History
Study completion expected
Primary completion expected
Started
Registered