Phase 4Not yet recruiting
Patient-centred Intervention With Virtual Support for Obesity and Kidney Transplant Access (PIVOT)
- Sponsor
- Kristin Clemens (Academic or other)
- Enrollment
- 880 planned
- Conditions
- Obesity; Chronic Kidney Disease; Chronic Renal Disease; CKD
- Interventions
- Semaglutide; Virtual Weight Management Coaching
- Ages
- adults, older adults
- Registry
- NCT07858331
Full record on ClinicalTrials.gov
From the registry
Obesity has a serious impact on people's health and quality of life. For those with advanced kidney disease (i.e. approaching the need for dialysis), obesity is especially problematic - obesity can not only lead to worsening kidney function and kidney failure, but it can also prevent patients from receiving a lifesaving kidney transplantation due to concerns about operation risks. Unfortunately, there is an urgent need but no rigorously proven treatments to help people with advanced kidney disease lose weight effectively and safely. The investigative team is a large team of doctors, nurses, dieticians, exercise specialists, social scientists, and patients with a lived experience, have spent three years advancing research to help people with advanced kidney disease achieve a healthier body weight. They have created a special weight loss program that combines individualized coaching on diet and save activity with a medication proven to help people with healthier kidneys lose weight (i.e. Ozempic). This research program is called PIVOT: Patient-centred Intervention with Virtual…
Primary outcomes
- Change in Body Weight
History
Primary completion expected
Expected to start
Registered
In the news
TrialsNature Medicine (opens Nature Medicine in a new tab)
Randomized trial investigates kidney protective mechanisms of semaglutide in type 2 diabetes
Researchers examined semaglutide in type 2 diabetes patients using histology, multiparametric MRI, and transcriptomics to understand renal protection.
