No phaseCompleted
Tyrosine Vs Tacrolimus With NB-UVB in Vitiligo
Comparative Efficacy of Topical Tacrolimus Versus Tyrosine as Co-Therapy to NB-UVB in Vitiligo: A Randomized Intra-Individual Controlled Clinical Trial
- Sponsor
- Minia University (Academic or other)
- Enrolment
- 67 enrolled
- Conditions
- Vitiligo
- Interventions
- Narrowband UVB Phototherapy; Topical Tacrolimus 0.1% ointment; Topical Tyrosine 2% cream
- Ages
- adults, older adults
- Registry
- NCT07532330
Full record on ClinicalTrials.gov
From the registry
The goal of this clinical trial is to learn if adding topical tacrolimus or topical tyrosine to narrowband UVB phototherapy works to treat vitiligo in adults. It will also learn about the safety of both combinations. The main questions it aims to answer are: Which combination (UVB + tacrolimus or UVB + tyrosine) leads to greater skin repigmentation (color return) after 3 months of treatment? What side effects do participants experience with each combination? Researchers will compare three groups: UVB + tacrolimus, UVB + tyrosine, and UVB only to see which is more effective and safer. Participants will: Receive narrowband UVB phototherapy sessions two times per week at minimal erythema dose Apply either topical tacrolimus or topical tyrosine to their vitiligo patches twice daily Visit the clinic every one month for skin examination and photography Report any side effects or skin reactions
Primary outcomes
- Clinical Improvement grade
History
Last registry update
Registered
Study completion
Primary completion
Started