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Arthrocentesis-PRF Versus Botulinum Toxin for Management of ADDwR

A Comparative Study Between Arthrocentesis Combined With Intra-Articular Injectable Platelet-Rich Fibrin Versus Ultrasound-Guided Lateral Pterygoid Botulinum Toxin Injection For Management of Anterior Disc Displacement With Reduction

Sponsor
Suez Canal University (Academic or other)
Enrollment
20 enrolled
Conditions
Temporomandibular Joint Internal Derangement; Temporomandibular Joint Disorders; Temporomandibular Disorders (TMD); TMJ Pain
Interventions
Injectable Platelet-Rich Fibrin (I-PRF) Injection; Botulinum Toxin Type A (BOTOX) Injection
Ages
children, adults
Registry
NCT07385742

Full record on ClinicalTrials.gov

From the registry

Temporomandibular joint (TMJ) internal derangement is a common cause of temporomandibular disorders and is often associated with pain, restricted mandibular movement, joint sounds, and functional limitations during mastication and mouth opening. Various treatment modalities have been proposed to manage these symptoms, aiming to reduce pain and improve joint function. This randomized clinical study was conducted to compare the effectiveness of botulinum toxin type A (BOTOX) injection into the lateral pterygoid muscle versus intracapsular injection of injectable platelet-rich fibrin (I-PRF) in the management of TMJ internal derangement. A total of 20 patients diagnosed with TMJ internal derangement were randomly allocated into two equal groups. Group I received intracapsular I-PRF injections into the superior joint space of the temporomandibular joint, while group II received botulinum toxin injections into the lateral pterygoid muscle. Clinical evaluation was performed using subjective and objective parameters at one, three, and six months following treatment. Outcomes included…

Primary outcomes

  • Pain Score (Visual Analogue Scale, VAS)
  • Joint Sounds (Clicking) Assessment
  • MRI Assessment of Disc Position

History

  1. Last registry update

  2. Registered

  3. Study completion

  4. Primary completion

  5. Started