No phaseActive, not recruiting

Eccentric Cycling in Multiple Sclerosis Rehabilitation

Eccentric Cycling : a New Training Modality in Multiple Sclerosis Rehabilitation

Sponsor
University of Liege (Academic or other)
Enrolment
60 planned
Conditions
Multiple Sclerosis; Rehabilitation; Neuro-Degenerative Disease; Neurorehabilitation
Interventions
Eccentric training; Concentric training
Ages
adults, older adults
Registry
NCT07316764

From the registry

The project aims to optimise functional rehabilitation programmes for people with multiple sclerosis. Investigators are proposing eccentric cycling as a new exercise modality for treating these patients. Based on previous results in healthy subjects, investigators will attempt to define the optimal parameters of this new modality (in terms of duration, intensity, frequency, etc.). Investigators also aim to demonstrate the effectiveness of this training (compared to conventional training) in improving muscle function, functional capacity, perception of chronic fatigue, quality of life, physical condition, and neurological and cognitive function.

Primary outcomes

  • Maximal Isometric Force
  • Walking distance
  • Glial Fibrillary Acidic Protein (GFAP)
  • Neurofilament Light Chain (NfL)
Full record on ClinicalTrials.gov