No phaseActive, not recruiting
Eccentric Cycling in Multiple Sclerosis Rehabilitation
Eccentric Cycling : a New Training Modality in Multiple Sclerosis Rehabilitation
- Sponsor
- University of Liege (Academic or other)
- Enrolment
- 60 planned
- Conditions
- Multiple Sclerosis; Rehabilitation; Neuro-Degenerative Disease; Neurorehabilitation
- Interventions
- Eccentric training; Concentric training
- Ages
- adults, older adults
- Registry
- NCT07316764
From the registry
The project aims to optimise functional rehabilitation programmes for people with multiple sclerosis. Investigators are proposing eccentric cycling as a new exercise modality for treating these patients. Based on previous results in healthy subjects, investigators will attempt to define the optimal parameters of this new modality (in terms of duration, intensity, frequency, etc.). Investigators also aim to demonstrate the effectiveness of this training (compared to conventional training) in improving muscle function, functional capacity, perception of chronic fatigue, quality of life, physical condition, and neurological and cognitive function.
Primary outcomes
- Maximal Isometric Force
- Walking distance
- Glial Fibrillary Acidic Protein (GFAP)
- Neurofilament Light Chain (NfL)