No phaseCompletedAge-related condition
A Clinical Study to Evaluate the Efficacy of Native CT-II® in Individuals With Knee Osteoarthritis
A Randomized, Double-Blind, Placebo-Controlled, Parallel Design Clinical Study to Evaluate the Efficacy of Native CT-II® in Individuals With Knee Osteoarthritis
- Sponsor
- Vedic Lifesciences Pvt. Ltd. (Industry)
- Enrolment
- 114 enrolled
- Conditions
- Knee Osteoarthritis (OA)
- Interventions
- Native CT-II® (undenatured type II collagen); Glucosamine HCL + Chondroitin Sulphate (G+C) [Comparator]; Placebo [Microcrystalline Cellulose (MCC)
- Ages
- adults, older adults
- Registry
- NCT06917287
Full record on ClinicalTrials.gov
From the registry
This randomized, double-blind, placebo-controlled clinical study evaluates the efficacy of Native CT-II® (undenatured type II collagen) in individuals with knee osteoarthritis using a parallel design.Participants are assigned to one of three groups: Group 1 receives Native CT-II® (40 mg daily individed doses), Group 2 receives Glucosamine HCL + Chondroitin Sulphate (2700 mg daily as acomparator), and Group 3 receives a placebo (Microcrystalline Cellulose). All participants take threecapsules after breakfast and three after dinner for 90 days . The study aims to screen approximately 142 participants , randomizing around 114 (considering a 20% dropout rate), with a target of 90completed participants (30 per group). Osteoarthritis (OA) is a degenerative joint disorder causing pain, stiffness, and reduced mobility,primarily affecting older adults. It is a leading cause of disability, with knee OA being the mostprevalent form. The global burden of OA is rising due to aging populations and increasing obesityrates, necessitating improved treatment options. Current management focuses on…
Primary outcomes
- To evaluate the effect of consumption of Native CT-II on knee joint health asassessed by change in modified Western Ontario and McMaster UniversityOsteoarthritis Index total score as compared to baseline,Glucosamine HCL + Chondroitin Sulphate an
History
Last registry update
Primary completion
Started
Registered