No phaseRecruitingAge-related condition
The Effect of Combination of Mediterranean Diet and Oleocanthal in Patients With Mild Cognitive Impairment (MeDi-SUPOL)
- Sponsor
- Aristotle University Of Thessaloniki (Academic or other)
- Enrolment
- 200 planned
- Conditions
- Mild Cognitive Impairment
- Interventions
- SUPOL; Dietary Pattern: MeDi
- Ages
- adults, older adults
- Registry
- NCT06705738
Full record on ClinicalTrials.gov
From the registry
BACKGROUND: Mild cognitive impairment (MCI) constitutes a form of preclinical dementia and characterizes a cognitive decline that exceeds what is expected for one's age and education status, but at the same time does not fulfill the criteria for dementia. MCI is considered a prodromal stage of Alzheimer's disease (AD) and the progression to this neurodegenerative disease, renders the patients heavily dependent on their relatives and the society, which creates a huge psychological and financial burden, since no effective treatment exists for MCI and AD to this day. Mediterranean diet (MeDi) displays beneficial effects on the cognitive function of both healthy individuals and cognitive impaired patients. High Phenolic Early Harvest Extra Virgin Olive Oil (HP-EH-EVOO) is a natural product that contains high concentrations of the substance Oleocanthal (OLC), while at the same time it has been shown to exert beneficial properties on the cognitive function of cognitive impaired individuals, as well as on the slowing down of the decline of cognitive function. AIM: The main hypothesis that…
Primary outcomes
- ADAS-Cog - Measurement to Assess the Severity of Cognitive Impairment
- MMSE - Measurement to Assess and Evaluate Cogntive Function
History
Study completion expected
Primary completion expected
Last registry update
Started
Registered