No phaseRecruitingAge-related condition

Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential Analysis (PI-PEG)

Sponsor
Centre Hospitalier Universitaire Dijon (Academic or other)
Enrolment
66 planned
Conditions
Idiopathic Parkinson's Disease and Lewy Body Disease
Interventions
Fasting blood test; Subject interview; Motor assessment; Neurocognitive assessment; Nutritional assessment; Taste tests
Ages
adults, older adults
Registry
NCT06439355

Full record on ClinicalTrials.gov

From the registry

The aim of the PI-PEG study is to explore the taste functions of the following 3 groups of participants: * healthy volunteers * patients with early Parkinson's disease * patients with incipient Lewy body disease. To this end, the results obtained from taste evoked potentials in each of the 3 groups of participants will be compared with each other and with different nutritional, motor and cognitive data. This study could reveal a difference in cortical processing of gustatory sensory information between patients who have had idiopathic Parkinson's disease progressing for 3 years or less, and patients who have had Lewy body disease progressing for 3 years or less. Indeed, a modification of taste evoked potentials (in terms of latencies) proportional to the degree of cerebral degeneration could be observed.

Primary outcomes

  • Average latency of taste-evoked potentials

History

  1. Primary completion expected

  2. Last registry update

  3. Registered

  4. Started