No phaseRecruitingHealthspan endpoint
Supramaximal High-Intensity Interval Training in People With and Without Chronic Obstructive Pulmonary Disease (COPD-HIIT)
Effects and Mechanisms of Supramaximal High-Intensity Interval Training in People With and Without Chronic Obstructive Pulmonary Disease on Extrapulmonary Manifestations
- Sponsor
- Umeå University (Academic or other)
- Enrollment
- 208 planned
- Conditions
- COPD; Healthy Controls
- Interventions
- Exercise training on a stationary bicycle
- Ages
- adults, older adults
- Registry
- NCT06068322
Full record on ClinicalTrials.gov
From the registry
Beyond pulmonary complications, COPD presents with extrapulmonary manifestations including reduced cognitive, cardiovascular, and muscle function. While exercise training is the cornerstone in the non-pharmacological treatment of COPD, there is a need for new exercise training methods. The COPD-HIIT trial intend to investigate the effects and mechanisms of 12 weeks supramaximal high-intensity interval-training (HIIT) compared to moderate intensive continous training (MICT) in people with COPD and matched healthy controls on important clinical outcomes. The trial also intends to compare the effects of 24 months of exercise training (supramaximal HIIT or MICT) to usual care in people with COPD on brain health, cardiorespiratory fitness and muscle power; in people with COPD.
Primary outcomes
- Change from baseline global cognitive function
- Change from baseline cardiorespiratory fitness
- Change from baseline quadriceps muscle power
History
Primary completion expected
Last registry update
Started
Registered