No phaseActive, not recruitingGeroscience intervention
Prandial Metabolic Phenotype in Adults
- Sponsor
- Texas A&M University (Academic or other)
- Enrolment
- 38 enrolled
- Conditions
- Protein Metabolism
- Interventions
- Total Amino Acids; Essential Amino Acids; Essential Amino Acids + Hydroxy-methylbutyric acid (HMB); Essential Amino Acids + Leucine; Essential Amino Acids High; Placebo Water
- Ages
- adults, older adults
- Registry
- NCT05400733
Full record on ClinicalTrials.gov
From the registry
Previous studies suggest that changes in metabolism due to the effects of aging might serve as a potential for therapeutic agents. The investigating lab developed a pulse method combining multiple stable isotopes to study multiple metabolic pathways in the same individual simultaneously. By measuring whole-body metabolism in a large group of older adults, the investigators may be able to unravel age-related deterioration in protein turnover (synthesis and breakdown) that contributes to impaired functional capacity. Metabolic profiles could explain differences in pathways in the aging process with special interest in metabolism of amino acids as they have been associated with aging-related disorders.
Primary outcomes
- Feeding related changes in whole-body protein and amino acid metabolism
History
Primary completion expected
Last registry update
Started
Registered