No phaseCompleted
Pre-eclampsia and Future Cardiovascular Health: An Underused Opportunity to Improve Family Health (FINNCARE)
- Sponsor
- Helsinki University Central Hospital (Academic or other)
- Enrolment
- 284 enrolled
- Conditions
- Pre-Eclampsia; Cardiovascular Diseases; Cardiovascular Risk Factor; Gestational Hypertension
- Interventions
- Face-to-face and web-based lifestyle intervention
- Ages
- children, adults, older adults
- Registry
- NCT04676295
Full record on ClinicalTrials.gov
From the registry
Background: PE (pre-eclampsia) is a common pregnancy-specific vascular hypertensive disease affecting 3-5% of pregnancies. PE independently increases the risk for premature cardiovascular disease (CVD) in mothers and their offspring long-term. PE provides a unique window for early risk profiling and CVD prevention. However, the efficacy of a family oriented lifestyle intervention to lower CVD risk in families with history of PE has not previously been evaluated. Aim: This study will explore the impact of PE on CVD progression 8-12 years from delivery in mothers and their children, and assess whether a lifestyle intervention is useful for lowering mother and child blood pressure and improving the CVD risk profile overall in families with a history of PE. Hypothesis: PE is related with CVD progression mediated by elevated blood pressure. Blood pressure and the CVD risk profile overall is modifiable in mothers and children by a 12-month behavioral lifestyle intervention in families with a history of PE. Study design: Randomized controlled behavioral lifestyle intervention trial…
Primary outcomes
- Blood pressure (mothers)
- Blood pressure (children)
History
Last registry update
Study completion
Primary completion
Registered
Started