No phaseCompletedAge-related condition
High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Early Alzheimer's Disease
- Sponsor
- Anhui Medical University (Academic or other)
- Enrolment
- 60 enrolled
- Conditions
- Transcranial Direct Current Stimulation; Functional Magnetic Resonance Imaging; Early Alzheimer's Disease
- Interventions
- HD-tDCS; computer-based cognitive training; Sham tDCS; Control cognitive training
- Ages
- adults, older adults
- Registry
- NCT04599764
Full record on ClinicalTrials.gov
From the registry
This completed randomized trial evaluated the clinical and neural effects of high-definition transcranial direct current stimulation (HD-tDCS) combined with computerized cognitive training in patients with Alzheimer's disease. Participants were assigned to active HD-tDCS plus computerized cognitive training, computerized cognitive training control, or active HD-tDCS control. The study assessed whether combined neuromodulation and cognitive training produced greater cognitive and clinical benefit than either component condition, and whether treatment-related benefit was associated with changes in brain network organization.
Primary outcomes
- Changes assessed by Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog)
History
Last registry update
Primary completion
Started
Registered