Impact of Anesthesia Maintenance Methods on Incidence of Postoperative Delirium

Surgery is one of the major treatment methods for patients with malignant tumor. And, alone with ageing process, more and more elderly patients undergo surgery for malignant tumor. Evidence emerges that choice of anesthetics, i.e., either inhalational or intravenous anesthetics, may influence the outcome of elderly patients undergoing cancer surgery. Delirium is a commonly occurred early postoperative cognitive complication in the elderly, and its occurrence is associated with the worsening outcomes. Choice anesthetics may influence the occurrence of postoperative delirium. However, evidence in this aspect is conflicting.

• Incidence of delirium within 7 days after surgery.

1. Last registry update

   Mar 4, 2022

2. Study completion

   Nov 26, 2017

3. Primary completion

   Sep 29, 2017

4. Registered

   Jan 25, 2016

5. Started

   Apr 1, 2015

• Intraoperative hypotension is associated with decreased long-term survival in older patients after major noncardiac surgery: Secondary analysis of three randomized trials

  Journal of clinical anesthesia

• Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial

  British journal of anaesthesia

• Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial

  BMJ open