American Journal of Physiology Heart and Circulatory Physiology
Mitochondrial proteostasis is impaired in mouse heart failure
Aged mice on a high-fat diet and L-NAME showed impaired mitochondrial proteostasis rather than defective biogenesis, suggesting quality control may contribute to reduced…Aged mice on a high-fat diet and L-NAME showed impaired mitochondrial proteostasis rather than defective biogenesis, suggesting quality control may contribute to reduced cardiac reserve.
Experiments in miceProteostasis