bioRxiv
Androgen receptor polyglutamine tract controls muscle growth and atrophy pathways
Researchers found that expanding polyglutamine tracts in the androgen receptor shift binding toward senescence-linked enhancers, driving muscle atrophy in cells and mice.Researchers found that expanding polyglutamine tracts in the androgen receptor shift binding toward senescence-linked enhancers, driving muscle atrophy in cells and mice.
Preprint: experiments in human cellsMuscle