Papers by Jie Zhu

3 results

  1. Frontiers in Aging Neuroscience

    Spinal fluid protein linked to Alzheimer’s dementia risk

    An observational study of 444 people without dementia linked a blood vessel-related protein to poorer thinking, brain shrinkage and later Alzheimer’s dementia.An observational study of 444 people without dementia linked a blood vessel-related protein to poorer thinking, brain shrinkage and later Alzheimer’s dementia.

    Cohort study of 444 peopleAlzheimer's disease
  2. Advanced Science

    Synthetic gene circuit clears protein aggregates and extends lifespan in Huntington disease mice

    The sensor-driven system selectively triggers autophagy regulator TFEB upon detecting toxic huntingtin conformers, lowering brain inflammation and rescuing synaptic…The sensor-driven system selectively triggers autophagy regulator TFEB upon detecting toxic huntingtin conformers, lowering brain inflammation and rescuing synaptic deficits.

    Experiments in miceHuntington's disease