Nutrients

Walnuts had little effect on body fat and weight in older adults

In a two-year randomized controlled trial of 326 healthy older adults, daily walnuts had little effect on body composition compared with avoiding walnuts.

Paper by Emilio Ros, Sheila López-Ruiz, Aleix Sala-Vila, +7 more authorsGemma Chiva-Blanch · Hospital Clínic de Barcelona · Instituto de Salud Carlos III (ISCIII)
Fat tissue clusters with similarly sized cells face each other, with walnut halves beside one cluster and small upright human figures beside both.
Studied:
Randomized trial in 326 healthy older adults, against adults following usual diets without walnuts (Blinded, sample size calculated, registered NCT01634841)
What changed:
Body weight and body fat did not differ between older adults eating walnuts and those avoiding walnuts
The catch:
The California Walnut Commission sponsored the trial and supplied the walnuts
In the record:
The 9th paper on walnuts with results in people; 16 on record in all.

Editor of record: Boris Djordjevic · AgingResearch.News

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The analysis included 326 healthy adults aged 63–79, including 220 women, in Barcelona, Spain, who completed a two-year randomized controlled trial. Participants added 30–60 grams of walnuts daily to their usual diet, or avoided walnuts. The walnut group received no advice to replace other foods or restrict calories. Scans measured body fat and fat-free tissue before and after the intervention.

Walnuts had little effect on body composition compared with the control diet, including no differences in weight, total fat or fat-free tissue. Women eating walnuts had a small increase in the ratio of abdominal to hip-and-thigh fat percentages. An exploratory analysis found adverse body composition changes in men with one version of FTO, an obesity-linked gene, compared with men carrying another version on the walnut diet. That subgroup was small.

Why it matters

For older adults, the trial addressed whether adding fat-rich walnuts to the usual diet contributes to the body fat changes that accompany aging.

Caveats

The authors note that this analysis covered only healthy older adults at the Barcelona site; results might differ in younger people or with other regional diets.

Where the evidence stands

Walnuts

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 6 independent labs in 4 countries
  • 7 trials
  • Funders: California Walnut Commission and others
  • 3 of 17 findings with company ties

From the paper

Participants

As pre-specified in the design of the WAHA trial [15], changes in body weight and BMI were the primary outcome, and changes in body composition by DXA were a secondary outcome at the Barcelona node, where 352 subjects were randomized.

Methods, 2.5. Statistical Analyses

Limitation

This was a secondary, pre-specified outcome limited to the Barcelona node of the WAHA trial, involving healthy elderly participants.

4. Discussion

Quoted word for word from the full text on mdpi.com.

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