Social network intervention

Intervention1 paper3 findings

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

1 lab in 1 country1 finding against
  • Human trial1

Outcomes

2

Cardiovascular risk

no changein humans1downin humans1

1 study
  1. Social network intervention has no effect on cardiovascular risk in humans (Risk-score change: 0.5 [1.9] versus 0.3 [1.8]; P = .38).

    Human trialHispanic and Somali adults; compared with delayed-intervention controlscommunity-based intervention delivered by lay health promoters12 monthsn = 475

    Social network intervention for cardiovascular risk reduction among Hispanic and Somali adults: a cluster randomized trial · Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 7 Jan 2026

  2. Social network intervention decreases cardiovascular risk in humans (Risk-score change: 0.4 [1.8] versus -0.1 [1.7]; P = .03).

    Human trialHispanic and Somali adults; compared with delayed-intervention controlscommunity-based intervention delivered by lay health promoters6 monthsn = 475

    Social network intervention for cardiovascular risk reduction among Hispanic and Somali adults: a cluster randomized trial · Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 7 Jan 2026

Proportion achieving >5% body weight loss

upin humans1

1 study
  1. Social network intervention increases proportion achieving >5% body weight loss in humans (37% [15] versus 18% [7.9]; P = .02).

    Human trialHispanic and Somali adults; compared with delayed-intervention controlscommunity-based intervention delivered by lay health promoters12 monthsn = 475

    Social network intervention for cardiovascular risk reduction among Hispanic and Somali adults: a cluster randomized trial · Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 7 Jan 2026

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