Inhalation anesthesia

Inhalation anesthesia has been studied in 2 papers since 2024: 1 observational study in people, 1 review; 1 in the past year. The newest paper, Nov 12, 2025: “The effect of intravenous anesthesia on postoperative cognitive function in patients undergoing painless gastroscopy: a meta-analysis”.

Exposure

2 papers study it4 findingsUpdated

See all 2

“there was no association between the type of anaesthetic agent and 1-yr mortality (hazard ratio=0.95; 95% confidence interval [CI] 0.84-1.08).”
Effects of inhalation versus total intravenous anaesthesia on long-term mortality in older patients after noncardiac surgery: a retrospective observational studyBritish journal of anaesthesia2024doi:10.1016/j.bja.2024.07.008

None of its findings points the other way.

  • 1 lab
  • Humans1

What did studies of Inhalation anesthesia find?

1

Studies of Inhalation anesthesia measured 1 outcome; the most studied are mortality (1 study).

Mortality

no changein humans1HR 0.95

1 study
  1. Inhalation anesthesia has no effect on mortality in humans (HR 0.95, 95% CI 0.84-1.08).

    “there was no association between the type of anaesthetic agent and 1-yr mortality (hazard ratio=0.95; 95% confidence interval [CI] 0.84-1.08).”

    Humansnoncardiac surgery under general anaesthesia (for ≥2 h)1 yrn = 45,879

    Effects of inhalation versus total intravenous anaesthesia on long-term mortality in older patients after noncardiac surgery: a retrospective observational study

    British journal of anaesthesia

What is Inhalation anesthesia linked with?

3

Studies link Inhalation anesthesia with 3 measures, most often acute kidney injury (1 study), perioperative adverse cardiovascular events (1) and postoperative pulmonary complications (1).

Acute kidney injury

upin humans1OR 2.19

1 study
  1. Inhalation anesthesia raises the risk of acute kidney injury in humans (OR 2.19, 95% CI 1.88-2.57).

    “and OR=2.19; 95% CI 1.88-2.57 for acute kidney injury).”

    Humansnoncardiac surgery under general anaesthesia (for ≥2 h)n = 45,879

    Effects of inhalation versus total intravenous anaesthesia on long-term mortality in older patients after noncardiac surgery: a retrospective observational study

    British journal of anaesthesia

More on Acute kidney injury

Perioperative adverse cardiovascular events

upin humans1OR 1.34

1 study
  1. Inhalation anesthesia raises the risk of perioperative adverse cardiovascular events in humans (OR 1.34, 95% CI 1.22-1.48).

    “OR=1.34; 95% CI 1.22-1.48 for perioperative adverse cardiovascular events”

    Humansnoncardiac surgery under general anaesthesia (for ≥2 h)n = 45,879

    Effects of inhalation versus total intravenous anaesthesia on long-term mortality in older patients after noncardiac surgery: a retrospective observational study

    British journal of anaesthesia

More on Perioperative adverse cardiovascular events

Postoperative pulmonary complications

upin humans1OR 1.3

1 study
  1. Inhalation anesthesia raises the risk of postoperative pulmonary complications in humans (OR 1.30, 95% CI 1.22-1.37).

    “inhalation anaesthesia was associated with increased risk of postoperative complications (odds ratio [OR]=1.30; 95% CI 1.22-1.37 for postoperative pulmonary complications”

    Humansnoncardiac surgery under general anaesthesia (for ≥2 h)n = 45,879

    Effects of inhalation versus total intravenous anaesthesia on long-term mortality in older patients after noncardiac surgery: a retrospective observational study

    British journal of anaesthesia

More on Postoperative pulmonary complications

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Nov 2025: 1Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 paper in 12 months