Neuro-Oncology
Older mice with brain tumors had poorer immune-cell drainage
Brain-tumor experiments compared mice aged 85–90 weeks with mice aged 6–8 weeks; older mice had shorter survival and signs suggesting impaired drainage around the brain.Brain-tumor experiments compared mice aged 85–90 weeks with mice aged 6–8 weeks; older mice had shorter survival and signs suggesting impaired drainage around the brain.
Mouse studyImmune response
Who was studiedAged mice with implanted glioblastoma, against young mice
What changedOlder tumor-bearing mice accumulated more bead-carrying immune cells around the brain than young mice
The catchImmune-cell buildup and VEGFR3 expression served as indirect indicators of impaired drainage