Papers on PARTASR

2 papers2 new in 30 days

Friday, November 13

bioRxivNov 13

Engineered tool improves DNA editing in mammalian cells

Editing efficiency rose from 4.29% with the original tool to 48.94% with the engineered version in experiments with mammalian cells.Editing efficiency rose from 4.29% with the original tool to 48.94% with the engineered version in experiments with mammalian cells.

A large dark blue-green cell contains a joined protein and cut DNA strands, surrounded by smaller cells with mostly intact strands.

Preprint: animal cell studyInterventions

Paper

Tuesday, November 10

Research SquareNov 10

Compact gene editor enables efficient DNA editing in mice

Viral delivery of the editor in mice reduced a cholesterol-regulating protein by about 82% and LDL cholesterol by about 47%.Viral delivery of the editor in mice reduced a cholesterol-regulating protein by about 82% and LDL cholesterol by about 47%.

Mouse livers beside a laboratory mouse, with sparse protein and cholesterol particles around the dark blue-green liver and dense particles around the gray…

Preprint: mouse studyInterventions

Paper