Frontiers in Aging
Metformin showed little benefit for flu immunity in aged mice
Six weeks of metformin before flu infection, continued for 10 days afterward, did not improve lung immune memory in aged male mice.Six weeks of metformin before flu infection, continued for 10 days afterward, did not improve lung immune memory in aged male mice.
Mouse studyMetformin
Who was studiedYoung and aged male mice, against aged control-treated mice
What changedLung memory T cell populations did not improve in metformin-treated aged mice compared with aged controls
The catchMetformin was stopped before secondary infection; protection with continued treatment was not measured