Criteria-based probable REM sleep behaviour disorder

Biomarker1 paper2 findings

  • Humans1

Effects

1

Dementia

no changein humans1HR 1

1 study
  1. Criteria-based probable REM sleep behaviour disorder has no effect on dementia in humans (HR 1.00, 95% CI: 0.57–1.76).

    “there was no association with all-cause dementia (HR 1.00, 95% CI: 0.57–1.76)”

    Humansmemory clinic cohortmedian follow-up 3.4 yearsn = 619

    Probable REM sleep disorder links to Lewy body dementia · Alzheimer's research & therapy · 2 Oct 2026

Dementia →

Associations

1

Lewy body dementia

upin humans1HR 4.82

1 study
  1. Criteria-based probable REM sleep behaviour disorder raises the risk of Lewy body dementia in humans (cause-specific HR 4.82, 95% CI: 1.54–15.10).

    “cause-specific hazard ratio [HR] 4.82, 95% CI: 1.54–15.10”

    Humansmemory clinic cohortmedian follow-up 3.4 yearsn = 619

    Probable REM sleep disorder links to Lewy body dementia · Alzheimer's research & therapy · 2 Oct 2026

Lewy body dementia →

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Alzheimer's Research & TherapyHumans

Probable REM sleep disorder links to Lewy body dementia

In a memory clinic cohort, probable REM sleep behaviour disorder was linked to incident Lewy body dementia with a hazard ratio of 4.82.In a memory clinic cohort, probable REM sleep behaviour disorder was linked to incident Lewy body dementia with a hazard ratio of 4.82.