1:"/_next/static/chunks/32kdba7gqz9qf.js?dpl=8a5da8a7dbde" 2:"/_next/static/chunks/2nmxk_o1w34yf.js?dpl=8a5da8a7dbde" 3:"/_next/static/chunks/1xm62ktiw3pge.js?dpl=8a5da8a7dbde" 4:"/_next/static/chunks/3pvuu255-wbub.js?dpl=8a5da8a7dbde" 5:"/_next/static/chunks/0e01mu_1b1vnc.js?dpl=8a5da8a7dbde" 6:"/_next/static/chunks/0p47z0h6ygcs3.js?dpl=8a5da8a7dbde" 7:"HTTPAccessFallbackBoundary" 8:I[768017,["$1","$2","$3","$4","$5","$6"],"$7"] 1c:"/_next/static/chunks/2mirth5tq5-kv.js?dpl=8a5da8a7dbde" 1d:I[253348,["$1","$2","$3","$4","$5","$6","$1c"],"default"] :HL["/_next/static/chunks/2d6mxl0qn36_g.css?dpl=8a5da8a7dbde","style"] :HL["/_next/static/chunks/172e6k_lih7k8.css?dpl=8a5da8a7dbde","style"] :HL["/_next/static/media/3a11180d498b75c0-s.p.2028s2bhlck6k.woff2?dpl=8a5da8a7dbde","font",{"crossOrigin":"","type":"font/woff2"}] b:T10b4,{"@context":"https://schema.org","@graph":[{"@type":"NewsMediaOrganization","@id":"https://agingresearch.news/#organization","name":"AgingResearch.News","alternateName":["Aging Research News"],"url":"https://agingresearch.news","logo":"https://agingresearch.news/logo.png","description":"AgingResearch.News is the superintelligence for aging research. It reads every new paper, weighs the evidence, cites every claim and fits a feed to your work.","slogan":"Every new aging paper, judged on evidence, never on fame.","foundingDate":"2026-10-02","founder":{"@type":"Person","@id":"https://agingresearch.news/person/boris-djordjevic#person","name":"Boris Djordjevic","jobTitle":"Editor, AgingResearch.News","url":"https://agingresearch.news/person/boris-djordjevic","sameAs":["https://x.com/longevityboris"],"worksFor":{"@id":"https://agingresearch.news/#organization"}},"parentOrganization":{"@type":"Organization","name":"Paperfoot AI Pte. Ltd.","address":{"@type":"PostalAddress","addressCountry":"SG"}},"publishingPrinciples":"https://agingresearch.news/status#standards","correctionsPolicy":"https://agingresearch.news/status#standards","ethicsPolicy":"https://agingresearch.news/status#standards","verificationFactCheckingPolicy":"https://agingresearch.news/status#standards","noBylinesPolicy":"https://agingresearch.news/status#standards","actionableFeedbackPolicy":"https://agingresearch.news/status#standards","contactPoint":{"@type":"ContactPoint","contactType":"editorial","url":"https://agingresearch.news/contact"},"knowsAbout":[{"@type":"Thing","name":"Aging","sameAs":"https://en.wikipedia.org/wiki/Ageing"},{"@type":"Thing","name":"Geroscience","sameAs":"https://en.wikipedia.org/wiki/Geroscience"},{"@type":"Thing","name":"Life extension","sameAs":"https://en.wikipedia.org/wiki/Life_extension"},{"@type":"Thing","name":"Cellular senescence","sameAs":"https://en.wikipedia.org/wiki/Cellular_senescence"},{"@type":"Thing","name":"Epigenetic clock","sameAs":"https://en.wikipedia.org/wiki/Epigenetic_clock"},{"@type":"Thing","name":"mTOR","sameAs":"https://en.wikipedia.org/wiki/MTOR"},{"@type":"Thing","name":"Rapamycin","sameAs":"https://en.wikipedia.org/wiki/Sirolimus"},{"@type":"Thing","name":"Cellular reprogramming","sameAs":"https://en.wikipedia.org/wiki/Reprogramming"},{"@type":"Thing","name":"NAD+","sameAs":"https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide"},{"@type":"Thing","name":"Sirtuins","sameAs":"https://en.wikipedia.org/wiki/Sirtuin"},{"@type":"Thing","name":"Mitochondria","sameAs":"https://en.wikipedia.org/wiki/Mitochondria"},{"@type":"Thing","name":"Calorie restriction","sameAs":"https://en.wikipedia.org/wiki/Calorie_restriction"},{"@type":"Thing","name":"GLP-1 receptor agonists","sameAs":"https://en.wikipedia.org/wiki/GLP-1_receptor_agonist"},{"@type":"Thing","name":"Inflammaging","sameAs":"https://en.wikipedia.org/wiki/Inflammaging"},{"@type":"Thing","name":"Brain aging","sameAs":"https://en.wikipedia.org/wiki/Aging_brain"},{"@type":"Thing","name":"Biological aging","sameAs":"https://en.wikipedia.org/wiki/Senescence"},{"@type":"Thing","name":"Geroprotectors","sameAs":"https://en.wikipedia.org/wiki/Geroprotector"},{"@type":"Thing","name":"Biomarkers of aging","sameAs":"https://en.wikipedia.org/wiki/Biomarkers_of_aging"},{"@type":"Thing","name":"Gerontology","sameAs":"https://en.wikipedia.org/wiki/Gerontology"},{"@type":"Thing","name":"Longevity","sameAs":"https://en.wikipedia.org/wiki/Longevity"},{"@type":"Thing","name":"Bioinformatics","sameAs":"https://en.wikipedia.org/wiki/Bioinformatics"},{"@type":"Thing","name":"Biotechnology","sameAs":"https://en.wikipedia.org/wiki/Biotechnology"},{"@type":"Thing","name":"Health policy","sameAs":"https://en.wikipedia.org/wiki/Health_policy"}],"sameAs":["https://x.com/agingbrief","https://www.linkedin.com/company/agingresearch-news"]},{"@type":"WebSite","@id":"https://agingresearch.news/#website","url":"https://agingresearch.news","name":"AgingResearch.News","alternateName":["Aging Research News"],"description":"AgingResearch.News is the superintelligence for aging research. It reads every new paper, weighs the evidence, cites every claim and fits a feed to your work.","inLanguage":"en","publisher":{"@id":"https://agingresearch.news/#organization"}}]}11:X 18:[["children",{"s":"__PAGE__","h":1024,"d":{"r":"$L19","p":false,"v":null}}]] 16:[["children",{"s":{"n":"at","t":"oc","k":"","s":[]},"h":1024,"d":{"r":"$L17","p":false,"v":"$11"},"c":"$Q18"}]] 14:[["children",{"s":"papers","h":1024,"d":{"r":"$L15","p":false,"v":"$11"},"c":"$Q16"}]] 12:[["children",{"s":{"n":"key","t":"d","k":"brain-tissue-mineralization","s":[]},"h":1024,"d":{"r":"$L13","p":false,"v":"$11"},"c":"$Q14"}]] f:[["children",{"s":"biomarker","h":1024,"d":{"r":"$L10","p":false,"v":"$11"},"c":"$Q12"}],["sheet",{"s":"__DEFAULT__","h":1024,"d":{"r":"$L1a","p":false,"v":null}}]] 0:{"P":null,"c":["","biomarker","brain-tissue-mineralization","papers"],"q":"","i":false,"t":{"t":{"s":"","h":1040,"d":{"r":["$","$L8","c",{"notFound":[[["$","link","0",{"rel":"stylesheet","href":"/_next/static/chunks/2d6mxl0qn36_g.css?dpl=8a5da8a7dbde","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}],["$","link","1",{"rel":"stylesheet","href":"/_next/static/chunks/172e6k_lih7k8.css?dpl=8a5da8a7dbde","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}],["$","script","script-0",{"src":"/_next/static/chunks/32kdba7gqz9qf.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-1",{"src":"/_next/static/chunks/2nmxk_o1w34yf.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-2",{"src":"/_next/static/chunks/1xm62ktiw3pge.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-3",{"src":"/_next/static/chunks/3pvuu255-wbub.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-4",{"src":"/_next/static/chunks/0e01mu_1b1vnc.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-5",{"src":"/_next/static/chunks/0p47z0h6ygcs3.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}]],["$","html",null,{"lang":"en","className":"_0coOsG_className ujwUxa_variable FJdxoa_variable Q67yJW_variable","data-release":"aws 8a5da8a7","suppressHydrationWarning":true,"children":[["$","head",null,{"children":[["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var m=localStorage.getItem(\"arn.me\");if(m)document.documentElement.dataset.me=m}catch(e){}"}}],["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var s=sessionStorage,n=performance.getEntriesByType(\"navigation\")[0],q;try{q=JSON.parse(s.getItem(\"arn.arrivals\")||\"[]\")}catch(e){}if(!Array.isArray(q))q=[];q.push({path:location.pathname,referrer:document.referrer,search:location.search,started:s.getItem(\"arn.visit\")===\"1\",again:!!n&&(n.type===\"reload\"||n.type===\"back_forward\")});s.setItem(\"arn.arrivals\",JSON.stringify(q.slice(-20)));s.setItem(\"arn.visit\",\"1\")}catch(e){}"}}],["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var d=document.documentElement,o=false,s=null;try{s=sessionStorage;o=s.getItem(\"arn.offers\")===\"off\"}catch(e){}if(!o){var u=(new URLSearchParams(location.search).get(\"utm_source\")||\"\").trim().toLowerCase(),h=\"\",c=\"\",m=null;try{h=new URL(document.referrer).hostname.toLowerCase().replace(/^www\\./,\"\")}catch(e){}try{c=String(document.cookie||\"\")}catch(e){}c.split(\";\").forEach(function(x){var p=x.trim().split(\"=\");if(p[0]===\"arn_app\")m=/^[A-Z]{3}$/.test(p[1]||\"\")?p[1]:\"\"});o=[\"chatgpt\",\"chatgpt.com\",\"chat.openai.com\"].indexOf(u)>=0||[\"chatgpt.com\",\"chat.openai.com\",\"oaiusercontent.com\"].some(function(x){return h===x||h.slice(-x.length-1)===\".\"+x})||((m!==null||[\"arn-ios\",\"arn-android\"].indexOf(u)>=0)&&[\"USA\"].indexOf(m||\"\")<0);if(o&&s)try{s.setItem(\"arn.offers\",\"off\")}catch(e){}}if(o)d.dataset.offers=\"off\";try{if(localStorage.getItem(\"arn.billing\")===\"appstore\")d.dataset.proOffers=\"off\"}catch(e){}}catch(e){}"}}],["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var v=(new URLSearchParams(location.search).get(\"via\")||\"\").trim().toLowerCase();if(/^(?:[a-z]{1,12}-)?[a-z0-9]{8}$/.test(v))document.documentElement.dataset.joinOff=location.pathname}catch(e){}"}}],"$L9","$La"]}],["$","body",null,{"className":"min-h-dvh bg-paper font-sans text-ink","children":[["$","a",null,{"href":"#content","className":"skip-link","children":["$","span",null,{"data-t":"nav.skip","lang":"$undefined","children":["$","i",null,{"children":"Skip to content"}]}]}],["$","script",null,{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"$b"}}],"$Lc","$Ld",false]}]]}]],"children":["$0:t:t:d:r:props:notFound:0","$Le"]}],"p":false,"v":null},"c":"$Qf"},"h":{"r":"$L1b","p":false,"v":null}},"m":"$undefined","G":["$1d",["$L1e","$L1f","$L20"]],"S":true,"r":"$undefined","s":"$undefined","a":"$undefined","l":"$undefined","p":"$undefined","d":"$undefined"} 21:I[684230,["$1","$2","$3","$4","$5","$6"],"MeProvider"] 22:"/_next/static/chunks/2r3k3l6912phf.js?dpl=8a5da8a7dbde" 23:"/_next/static/chunks/1r4g9f64t24cy.js?dpl=8a5da8a7dbde" 24:"/_next/static/chunks/44mhdc4gpy07e.js?dpl=8a5da8a7dbde" 25:"/_next/static/chunks/3-_xi8j1vhyn_.js?dpl=8a5da8a7dbde" 26:"/_next/static/chunks/14i8xby-ioia8.js?dpl=8a5da8a7dbde" 27:I[432748,["$1","$2","$3","$4","$5","$6","$22","$23","$24","$25","$26"],"Unplaced"] 28:"/_next/static/chunks/1zjhs2xgoo-mz.js?dpl=8a5da8a7dbde" 29:I[675689,["$1","$2","$3","$4","$5","$6","$28","$23","$24","$25","$26"],"Rail"] 2a:I[435939,["$1","$2","$3","$4","$5","$6","$28","$23","$24","$25","$26"],"SiteHeader"] 2b:I[443567,["$1","$2","$3","$4","$5","$6","$22","$23","$24","$25","$26"],"NotFoundSearch"] 2c:I[522016,["$1","$2","$3","$4","$5","$6","$28","$23","$24","$25","$26"],""] 2e:I[149277,["$1","$2","$3","$4","$5","$6","$28","$23","$24","$25","$26"],"FoundingBar"] 2f:I[432384,["$1","$2","$3","$4","$5","$6","$28","$23","$24","$25","$26"],"TrialOfferSheet"] 30:I[36861,["$1","$2","$3","$4","$5","$6","$28","$23","$24","$25","$26"],"SharedBy"] 32:I[936821,["$1","$2","$3","$4","$5","$6"],"AuthHost"] 33:I[188415,["$1","$2","$3","$4","$5","$6"],"BottomTabBar"] 34:I[233785,["$1","$2","$3","$4","$5","$6"],"FeedTracker"] 35:I[696255,["$1","$2","$3","$4","$5","$6"],"NavMemory"] 36:I[918962,["$1","$2","$3","$4","$5","$6"],"SurfaceMemory"] 37:I[124213,["$1","$2","$3","$4","$5","$6"],"PageviewBeacon"] 3d:"$Sreact.fragment" 3e:I[339756,["$1","$2","$3","$4","$5","$6"],"default"] 3f:I[837457,["$1","$2","$3","$4","$5","$6"],"default"] 41:I[897367,["$1","$2","$3","$4","$5","$6"],"OutletBoundary"] 43:"ViewportBoundary" 44:I[897367,["$1","$2","$3","$4","$5","$6"],"$43"] 46:"MetadataBoundary" 47:I[897367,["$1","$2","$3","$4","$5","$6"],"$46"] 48:"$Sreact.suspense" :HL["/_next/static/chunks/29t1egu1vjhdp.css?dpl=8a5da8a7dbde","style"] c:["$","$L21",null,{"children":[[[],[["$","$L27",null,{"children":["$","div",null,{"className":"frame","data-wide":"$undefined","children":[["$","$L29",null,{"hint":"$undefined","updatesAt":"2026-10-26T17:10:00+00:00"}],["$","div",null,{"className":"frame-column min-w-0","children":[[["$","$L2a",null,{"hint":"$undefined"}],["$","div",null,{"id":"content","tabIndex":-1,"className":"outline-none"}]],["$","main",null,{"className":"min-w-0 px-(--col-pad) lg:pb-16 pt-4 md:pt-5","children":[["$","header",null,{"className":"bleed flex items-end justify-between gap-6 border-b border-rule px-(--col-pad) pb-3","children":[["$","div",null,{"className":"min-w-0","children":["$undefined",["$","h1",null,{"className":"headline text-[22px] leading-[1.15] font-extrabold tracking-[-0.02em] text-ink","children":["$","span",null,{"data-t":"not-found.title","lang":"$undefined","children":["$","i",null,{"children":"Page not found"}]}]}],"$undefined"]}],"$undefined"]}],["$","p",null,{"className":"mt-4 text-[15px] leading-[1.4] text-pretty text-ink-soft","children":["$","span",null,{"data-t":"not-found.line","lang":"$undefined","children":["$","i",null,{"children":"The link may be old or mistyped."}]}]}],["$","$L2b",null,{}],["$","ul",null,{"className":"mt-6","children":[["$","li","/",{"children":["$","$L2c",null,{"href":"/","prefetch":false,"className":"bleed flex min-h-12 items-center border-b border-rule px-(--col-pad) text-[15px] font-bold transition-colors duration-[120ms] hover:bg-hover active:bg-pressed","children":["$","span",null,{"data-t":"nav.home","lang":"$undefined","children":["$","i",null,{"children":"Home"}]}]}]}],["$","li","/latest",{"children":["$","$L2c",null,{"href":"/latest","prefetch":false,"className":"bleed flex min-h-12 items-center border-b border-rule px-(--col-pad) text-[15px] font-bold transition-colors duration-[120ms] hover:bg-hover active:bg-pressed","children":["$","span",null,{"data-t":"nav.latest","lang":"$undefined","children":["$","i",null,{"children":"Latest"}]}]}]}],["$","li","/topics",{"children":["$","$L2c",null,{"href":"/topics","prefetch":false,"className":"bleed flex min-h-12 items-center border-b border-rule px-(--col-pad) text-[15px] font-bold transition-colors duration-[120ms] hover:bg-hover active:bg-pressed","children":["$","span",null,{"data-t":"nav.topics","lang":"$undefined","children":["$","i",null,{"children":"Topics"}]}]}]}]]}]]}],"$L2d",["$","$L2e",null,{"until":"2026-11-30T23:59:59.000Z"}],["$","$L2f",null,{}]]}],["$","$L30",null,{}],"$L31"]}]}],"$c:props:children:0:0"]],"$undefined",["$","$L32",null,{"oneTapClientId":"1014590465548-acrir82hrkhsm9kpku98fp77435bh7qo.apps.googleusercontent.com"}],["$","$L33",null,{}],["$","$L34",null,{}],["$","$L35",null,{}],["$","$L36",null,{"surface":"site"}]]}] d:["$","$L37",null,{}] 3a:T10b4,{"@context":"https://schema.org","@graph":[{"@type":"NewsMediaOrganization","@id":"https://agingresearch.news/#organization","name":"AgingResearch.News","alternateName":["Aging Research News"],"url":"https://agingresearch.news","logo":"https://agingresearch.news/logo.png","description":"AgingResearch.News is the superintelligence for aging research. It reads every new paper, weighs the evidence, cites every claim and fits a feed to your work.","slogan":"Every new aging paper, judged on evidence, never on fame.","foundingDate":"2026-10-02","founder":{"@type":"Person","@id":"https://agingresearch.news/person/boris-djordjevic#person","name":"Boris Djordjevic","jobTitle":"Editor, AgingResearch.News","url":"https://agingresearch.news/person/boris-djordjevic","sameAs":["https://x.com/longevityboris"],"worksFor":{"@id":"https://agingresearch.news/#organization"}},"parentOrganization":{"@type":"Organization","name":"Paperfoot AI Pte. Ltd.","address":{"@type":"PostalAddress","addressCountry":"SG"}},"publishingPrinciples":"https://agingresearch.news/status#standards","correctionsPolicy":"https://agingresearch.news/status#standards","ethicsPolicy":"https://agingresearch.news/status#standards","verificationFactCheckingPolicy":"https://agingresearch.news/status#standards","noBylinesPolicy":"https://agingresearch.news/status#standards","actionableFeedbackPolicy":"https://agingresearch.news/status#standards","contactPoint":{"@type":"ContactPoint","contactType":"editorial","url":"https://agingresearch.news/contact"},"knowsAbout":[{"@type":"Thing","name":"Aging","sameAs":"https://en.wikipedia.org/wiki/Ageing"},{"@type":"Thing","name":"Geroscience","sameAs":"https://en.wikipedia.org/wiki/Geroscience"},{"@type":"Thing","name":"Life extension","sameAs":"https://en.wikipedia.org/wiki/Life_extension"},{"@type":"Thing","name":"Cellular senescence","sameAs":"https://en.wikipedia.org/wiki/Cellular_senescence"},{"@type":"Thing","name":"Epigenetic clock","sameAs":"https://en.wikipedia.org/wiki/Epigenetic_clock"},{"@type":"Thing","name":"mTOR","sameAs":"https://en.wikipedia.org/wiki/MTOR"},{"@type":"Thing","name":"Rapamycin","sameAs":"https://en.wikipedia.org/wiki/Sirolimus"},{"@type":"Thing","name":"Cellular reprogramming","sameAs":"https://en.wikipedia.org/wiki/Reprogramming"},{"@type":"Thing","name":"NAD+","sameAs":"https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide"},{"@type":"Thing","name":"Sirtuins","sameAs":"https://en.wikipedia.org/wiki/Sirtuin"},{"@type":"Thing","name":"Mitochondria","sameAs":"https://en.wikipedia.org/wiki/Mitochondria"},{"@type":"Thing","name":"Calorie restriction","sameAs":"https://en.wikipedia.org/wiki/Calorie_restriction"},{"@type":"Thing","name":"GLP-1 receptor agonists","sameAs":"https://en.wikipedia.org/wiki/GLP-1_receptor_agonist"},{"@type":"Thing","name":"Inflammaging","sameAs":"https://en.wikipedia.org/wiki/Inflammaging"},{"@type":"Thing","name":"Brain aging","sameAs":"https://en.wikipedia.org/wiki/Aging_brain"},{"@type":"Thing","name":"Biological aging","sameAs":"https://en.wikipedia.org/wiki/Senescence"},{"@type":"Thing","name":"Geroprotectors","sameAs":"https://en.wikipedia.org/wiki/Geroprotector"},{"@type":"Thing","name":"Biomarkers of aging","sameAs":"https://en.wikipedia.org/wiki/Biomarkers_of_aging"},{"@type":"Thing","name":"Gerontology","sameAs":"https://en.wikipedia.org/wiki/Gerontology"},{"@type":"Thing","name":"Longevity","sameAs":"https://en.wikipedia.org/wiki/Longevity"},{"@type":"Thing","name":"Bioinformatics","sameAs":"https://en.wikipedia.org/wiki/Bioinformatics"},{"@type":"Thing","name":"Biotechnology","sameAs":"https://en.wikipedia.org/wiki/Biotechnology"},{"@type":"Thing","name":"Health policy","sameAs":"https://en.wikipedia.org/wiki/Health_policy"}],"sameAs":["https://x.com/agingbrief","https://www.linkedin.com/company/agingresearch-news"]},{"@type":"WebSite","@id":"https://agingresearch.news/#website","url":"https://agingresearch.news","name":"AgingResearch.News","alternateName":["Aging Research News"],"description":"AgingResearch.News is the superintelligence for aging research. It reads every new paper, weighs the evidence, cites every claim and fits a feed to your work.","inLanguage":"en","publisher":{"@id":"https://agingresearch.news/#organization"}}]}e:["$","html",null,{"lang":"en","className":"_0coOsG_className ujwUxa_variable FJdxoa_variable Q67yJW_variable","data-release":"aws 8a5da8a7","suppressHydrationWarning":true,"children":[["$","head",null,{"children":[["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var m=localStorage.getItem(\"arn.me\");if(m)document.documentElement.dataset.me=m}catch(e){}"}}],["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var s=sessionStorage,n=performance.getEntriesByType(\"navigation\")[0],q;try{q=JSON.parse(s.getItem(\"arn.arrivals\")||\"[]\")}catch(e){}if(!Array.isArray(q))q=[];q.push({path:location.pathname,referrer:document.referrer,search:location.search,started:s.getItem(\"arn.visit\")===\"1\",again:!!n&&(n.type===\"reload\"||n.type===\"back_forward\")});s.setItem(\"arn.arrivals\",JSON.stringify(q.slice(-20)));s.setItem(\"arn.visit\",\"1\")}catch(e){}"}}],["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var d=document.documentElement,o=false,s=null;try{s=sessionStorage;o=s.getItem(\"arn.offers\")===\"off\"}catch(e){}if(!o){var u=(new URLSearchParams(location.search).get(\"utm_source\")||\"\").trim().toLowerCase(),h=\"\",c=\"\",m=null;try{h=new URL(document.referrer).hostname.toLowerCase().replace(/^www\\./,\"\")}catch(e){}try{c=String(document.cookie||\"\")}catch(e){}c.split(\";\").forEach(function(x){var p=x.trim().split(\"=\");if(p[0]===\"arn_app\")m=/^[A-Z]{3}$/.test(p[1]||\"\")?p[1]:\"\"});o=[\"chatgpt\",\"chatgpt.com\",\"chat.openai.com\"].indexOf(u)>=0||[\"chatgpt.com\",\"chat.openai.com\",\"oaiusercontent.com\"].some(function(x){return h===x||h.slice(-x.length-1)===\".\"+x})||((m!==null||[\"arn-ios\",\"arn-android\"].indexOf(u)>=0)&&[\"USA\"].indexOf(m||\"\")<0);if(o&&s)try{s.setItem(\"arn.offers\",\"off\")}catch(e){}}if(o)d.dataset.offers=\"off\";try{if(localStorage.getItem(\"arn.billing\")===\"appstore\")d.dataset.proOffers=\"off\"}catch(e){}}catch(e){}"}}],["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var v=(new URLSearchParams(location.search).get(\"via\")||\"\").trim().toLowerCase();if(/^(?:[a-z]{1,12}-)?[a-z0-9]{8}$/.test(v))document.documentElement.dataset.joinOff=location.pathname}catch(e){}"}}],"$L38","$L39"]}],["$","body",null,{"className":"min-h-dvh bg-paper font-sans text-ink","children":[["$","a",null,{"href":"#content","className":"skip-link","children":["$","span",null,{"data-t":"nav.skip","lang":"$undefined","children":["$","i",null,{"children":"Skip to content"}]}]}],["$","script",null,{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"$3a"}}],"$L3b","$L3c",false]}]]}] 10:["$","$3d","c",{"children":[null,["$","$L3e",null,{"parallelRouterKey":"children","error":"$undefined","errorStyles":"$undefined","errorScripts":"$undefined","template":["$","$L3f",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$undefined","forbidden":"$undefined","unauthorized":"$undefined"}]]}] 13:["$","$3d","c",{"children":[null,["$","$L3e",null,{"parallelRouterKey":"children","error":"$undefined","errorStyles":"$undefined","errorScripts":"$undefined","template":["$","$L3f",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$undefined","forbidden":"$undefined","unauthorized":"$undefined"}]]}] 15:["$","$3d","c",{"children":[null,["$","$L3e",null,{"parallelRouterKey":"children","error":"$undefined","errorStyles":"$undefined","errorScripts":"$undefined","template":["$","$L3f",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$undefined","forbidden":"$undefined","unauthorized":"$undefined"}]]}] 17:["$","$3d","c",{"children":[null,["$","$L3e",null,{"parallelRouterKey":"children","error":"$undefined","errorStyles":"$undefined","errorScripts":"$undefined","template":["$","$L3f",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$undefined","forbidden":"$undefined","unauthorized":"$undefined"}]]}] 19:["$","$3d","c",{"children":["$L40",[["$","script","script-0",{"src":"/_next/static/chunks/1zjhs2xgoo-mz.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-1",{"src":"/_next/static/chunks/1r4g9f64t24cy.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-2",{"src":"/_next/static/chunks/44mhdc4gpy07e.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-3",{"src":"/_next/static/chunks/3-_xi8j1vhyn_.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}],["$","script","script-4",{"src":"/_next/static/chunks/14i8xby-ioia8.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}]],["$","$L41",null,{"children":"$@42"}]]}] 1a:["$","$3d","c",{"children":[null,null,null]}] 1b:["$","$3d","h",{"children":[null,["$","$L44",null,{"children":"$L45"}],["$","$L47",null,{"children":[["$","div",null,{"hidden":true,"children":["$","$48",null,{"name":"Next.Metadata","children":"$L49"}]}],"$L4a"]}],["$","meta",null,{"name":"next-size-adjust","content":""}]]}] 1e:["$","link","0",{"rel":"stylesheet","href":"/_next/static/chunks/2d6mxl0qn36_g.css?dpl=8a5da8a7dbde","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}] 1f:["$","link","1",{"rel":"stylesheet","href":"/_next/static/chunks/172e6k_lih7k8.css?dpl=8a5da8a7dbde","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}] 20:["$","link","2",{"rel":"stylesheet","href":"/_next/static/chunks/29t1egu1vjhdp.css?dpl=8a5da8a7dbde","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}] 4b:"/_next/static/chunks/0hfie3e-u_403.js?dpl=8a5da8a7dbde" 4c:I[408821,["$1","$2","$3","$4","$5","$6","$4b"],"default"] 4e:I[194008,["$1","$2","$3","$4","$5","$6"],"LangMarks"] 11:C 3b:["$","$L21",null,{"children":[["$","$L3e",null,{"parallelRouterKey":"children","error":"$4c","errorStyles":[],"errorScripts":[["$","script","script-0",{"src":"/_next/static/chunks/0hfie3e-u_403.js?dpl=8a5da8a7dbde","async":true,"nonce":"$undefined"}]],"template":["$","$L3f",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$c:props:children:0:1","forbidden":"$undefined","unauthorized":"$undefined"}],["$","$L3e",null,{"parallelRouterKey":"sheet","error":"$4c","errorStyles":"$3b:props:children:0:props:errorStyles","errorScripts":"$3b:props:children:0:props:errorScripts","template":["$","$L3f",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$undefined","forbidden":"$undefined","unauthorized":"$undefined"}],["$","$L32",null,{"oneTapClientId":"1014590465548-acrir82hrkhsm9kpku98fp77435bh7qo.apps.googleusercontent.com"}],["$","$L33",null,{}],["$","$L34",null,{}],["$","$L35",null,{}],["$","$L36",null,{"surface":"site"}]]}] 3c:["$","$L37",null,{}] 4d:T628,(()=>{try{var T=[["es-MX"],["pt-PT"],["en-US"],["en-GB","IE AU NZ"],["zh-Hans"],["zh-Hant"],["ja"],["ko"],["es-ES"],["it"],["de-DE"],["nl-NL"],["pt-BR"],["fr-FR"],["ru"]],k="6759aef8",d=document,h=d.documentElement,m=function g(a,b){for(let c=0;c=0)return b[a][0];null===e&&(e=b[a][0])}}if(null!==e)return e}return null},l=null,c=d.cookie.match(/(?:^|; )arn_lang=([^;]*)/);if(c){var v=decodeURIComponent(c[1]),i=v.lastIndexOf(".");if(/^(web|app|detected)$/.test(v.slice(i+1)))l=m([v.slice(0,i)],T)}if(!l){l=m(navigator.languages,T)||"en-US";d.cookie="arn_lang="+l+".detected;path=/;max-age=31536000;samesite=lax"}h.setAttribute("data-lang",l);if(l==="en-US")return;var p=l+"."+k+"\n",s=localStorage.getItem("arn.i18n"),e=d.createElement("style");if(s&&s.indexOf(p)===0){e.textContent=s.slice(p.length);d.head.appendChild(e);return}var f=()=>h.removeAttribute("data-lw"),n=d.createElement("link");h.setAttribute("data-lw","");setTimeout(f,1500);e.textContent="[data-lw] [data-t],[data-lw] [data-trich]{visibility:hidden}";d.head.appendChild(e);n.rel="stylesheet";n.href="/i18n/"+l+"."+k+".css";n.setAttribute("blocking","render");n.onerror=f;n.onload=()=>{f();try{localStorage.setItem("arn.i18n",p+Array.from(n.sheet.cssRules,r=>r.cssText).join("\n"))}catch{}};d.head.appendChild(n)}catch{}})()a:[["$","script",null,{"dangerouslySetInnerHTML":{"__html":"$4d"}}],["$","$L4e",null,{}]] 4f:T628,(()=>{try{var T=[["es-MX"],["pt-PT"],["en-US"],["en-GB","IE AU NZ"],["zh-Hans"],["zh-Hant"],["ja"],["ko"],["es-ES"],["it"],["de-DE"],["nl-NL"],["pt-BR"],["fr-FR"],["ru"]],k="6759aef8",d=document,h=d.documentElement,m=function g(a,b){for(let c=0;c=0)return b[a][0];null===e&&(e=b[a][0])}}if(null!==e)return e}return null},l=null,c=d.cookie.match(/(?:^|; )arn_lang=([^;]*)/);if(c){var v=decodeURIComponent(c[1]),i=v.lastIndexOf(".");if(/^(web|app|detected)$/.test(v.slice(i+1)))l=m([v.slice(0,i)],T)}if(!l){l=m(navigator.languages,T)||"en-US";d.cookie="arn_lang="+l+".detected;path=/;max-age=31536000;samesite=lax"}h.setAttribute("data-lang",l);if(l==="en-US")return;var p=l+"."+k+"\n",s=localStorage.getItem("arn.i18n"),e=d.createElement("style");if(s&&s.indexOf(p)===0){e.textContent=s.slice(p.length);d.head.appendChild(e);return}var f=()=>h.removeAttribute("data-lw"),n=d.createElement("link");h.setAttribute("data-lw","");setTimeout(f,1500);e.textContent="[data-lw] [data-t],[data-lw] [data-trich]{visibility:hidden}";d.head.appendChild(e);n.rel="stylesheet";n.href="/i18n/"+l+"."+k+".css";n.setAttribute("blocking","render");n.onerror=f;n.onload=()=>{f();try{localStorage.setItem("arn.i18n",p+Array.from(n.sheet.cssRules,r=>r.cssText).join("\n"))}catch{}};d.head.appendChild(n)}catch{}})()39:[["$","script",null,{"dangerouslySetInnerHTML":{"__html":"$4f"}}],["$","$L4e",null,{}]] 50:T5d5,(function(c){try{var d=document.documentElement,i,j,K=/^[a-z0-9-]{1,40}$/,own=function(o,k){return Object.prototype.hasOwnProperty.call(o,k)};for(i=0;i

Thursday, January 7

Brain tissues atrophy is not always the best structural biomarker of physiological aging: A multimodal cross-sectional study