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Biofidelic FEM-based probability of hip fracture

There is 1 paper on biofidelic FEM-based probability of hip fracture in aging research: 1 observational study in people. The newest story, Oct 30, 2026: “Computer model linked to future hip fracture risk”.

Biomarker

1 paper studies it3 findings

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“each 1-SD increase in PFx showed a comparable association (HR 5.70, p < 0.001)”
Biofidelic finite element models for personalized assessment of hip fracture riskJBMR plus2026doi:10.1093/jbmrpl/ziag178
  • Humans1

Effects

1

Hip fracture prediction discrimination

upin humans1

1 study

  1. Biofidelic FEM-based probability of hip fracture is linked with better hip fracture prediction discrimination in humans (KURE cohort; adjusted PFx compared with a clinical model of age, sex, and BMI) (C-index 0.900 versus 0.802).

    “Adjusted PFx showed a higher C-index (0.900) than the clinical model of age, sex, and BMI (0.802).”

    HumansKURE cohort; adjusted PFx compared with a clinical model of age, sex, and BMIn = 125

    Computer model linked to future hip fracture risk

    JBMR plus

Associations

2

Incident hip fractures

upin humans1HR 5.7

1 study

  1. Biofidelic FEM-based probability of hip fracture is associated with incident hip fractures in humans (KURE cohort; per 1-SD increase in PFx) (HR 5.70 per 1-SD increase; p < 0.001).

    “each 1-SD increase in PFx showed a comparable association (HR 5.70, p < 0.001)”

    HumansKURE cohort; per 1-SD increase in PFxn = 125

    Computer model linked to future hip fracture risk

    JBMR plus

More on Incident hip fractures

Hip fracture status

upin humans1

1 study

  1. Biofidelic FEM-based probability of hip fracture predicts hip fracture status in humans (Emilia-Romagna cohort) (AUC 0.77, 95% CI 0.63–0.89).

    “In Emilia-Romagna, PFx showed discrimination for fracture status (AUC 0.77, 95% CI 0.63–0.89) comparable to aBMD and S.”

    HumansEmilia-Romagna cohortfemalesn = 53

    Computer model linked to future hip fracture risk

    JBMR plus

More on Hip fracture status

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JBMR Plus

Computer model linked to future hip fracture risk

In the Korean cohort, the adjusted model’s risk-ranking score was 0.900, versus 0.802 for age, sex and body mass index, a weight-for-height measure.In the Korean cohort, the adjusted model’s risk-ranking score was 0.900, versus 0.802 for age, sex and body mass index, a weight-for-height measure.

Cohort · 125 peopleHip fracture
Paper

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