revumenib

AssetAlso called SNDX-50613 FREE BASE, SNDX-5613 Free Base, Revuforj

Inhibits menin to disrupt oncogenic transcription driven by KMT2A rearrangements.

Stage
Approved
Modality
Small molecule
Target
KMT2A
17
Indications
26
Trials
1
Developer

Approved by the FDA on Nov 15, 2024 (NDA218944). FDA

Indications

17
  • Relapsed or refractory acute leukemia with a KMT2A translocation

    Approved, FDA

  • Refractory Acute Leukemia

    Approved, FDA

  • Relapsed or refractory acute myeloid leukemia

    Approved, FDA

14 more

In the full profile

  • Target and mechanism2
  • Owner and partners1
  • Trials26
  • Evidence for its targets2
  • Competitors12
  • Aging relevance1
  • Signals3

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