No phaseEnrolling by invitation
Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer (IMNUTPREH-UGIC)
Nutritional Therapy in the Surgical Prehabilitation of Patients With Esophageal, Gastric, and Pancreatic Cancer to Assess the Reduction of Postoperative Complications and the Maintenance of Muscle Mass.
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal (Academic or other)
- Enrollment
- 110 planned
- Conditions
- Upper GI Cancer
- Interventions
- Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid); Standart of care
- Ages
- adults, older adults
- Registry
- NCT07884214
Full record on ClinicalTrials.gov
From the registry
Perioperative immunonutrition has been proposed as a strategy to modulate the inflammatory response and improve outcomes after upper GI surgery. However, clinical evidence is heterogeneous, and there are few studies that integrate morbidity outcomes with objective measures of body composition using computed tomography (CT). The objective was to compare immunonutrition versus standard enteral supplementation in surgically treated patients with upper GI cancer (gastric, esophageal, pancreatic), evaluating postoperativecomplications and changes in body composition.
Primary outcomes
- Post-surgical complications
History
Study completion expected
Primary completion expected
Registered
Started