Phase 1Completed
Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone
A Phase 1, Open-Label, Two-Part, Single-Sequence Study to Evaluate the Effect of Multiple Oral Doses of BEM/RZR FDC on the Pharmacokinetics of Buprenorphine/Naloxone or Methadone in Participants on Stable Maintenance Therapy for Opiate Withdrawal
- Sponsor
- Atea Pharmaceuticals, Inc. (Industry)
- Enrollment
- 30 enrolled
- Conditions
- Healthy Volunteer Study
- Interventions
- Buprenorphine/Naloxone + BEM/RZR; Methadone +BEM/RZR
- Ages
- adults, older adults
- Registry
- NCT07314346
Full record on ClinicalTrials.gov
From the registry
Drug-drug interaction study between Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone
Primary outcomes
- Effect of BEM/RZR on PK of buprenorphine,norbuprenorphine and naloxone
- Effect of BEM/RZR on PK of methadone
History
Last registry update
Primary completion
Registered
Started