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Phase 4Active, not recruitingHealthspan endpoint

A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment (GiCIIS)

Pragmatic Open-label, Parallel-group Clinical Trial on the Effectiveness of Extract of Ginkgo Biloba Leaves Tablets as add-on to Standard of Care in Participants With Cognitive Impairment After an Acute Ischemic Stroke (GiCIIS)

Sponsor
Dr. Willmar Schwabe GmbH & Co. KG (Industry)
Enrollment
400 planned
Conditions
Ischemic Stroke Hospitalized; Impairment, Cognitive
Interventions
Extract of Ginkgo Biloba Leaves Tablets 240 mg (2 x 40 mg, t.i.d.); Standard of care (SoC) Group
Ages
adults, older adults
Registry
NCT07220538, ChiCTR2500107051

Full record on ClinicalTrials.gov

From the registry

The goal of this clinical trial is to learn if Extract of Ginkgo Biloba Leaves Tablets help improve thinking and memory in people aged 55 years and older who had an ischemic stroke (a type of stroke caused by a blocked blood vessel in the brain). It will also look at how safe the Extract of Ginkgo Biloba Leaves Tablets are. The main questions it aims to answer are: * Do the Extract of Ginkgo Biloba Leaves Tablets help people with memory or thinking problems after an ischemic stroke? * What medical problems do people have when taking the Extract of Ginkgo Biloba Leaves Tablets ? Researchers will compare people who take the Extract of Ginkgo Biloba Leaves Tablets along with their usual post-stroke treatment to people who only receive their usual post-stroke treatment. Participants will: * Have had an ischemic stroke confirmed by MRI (Magnet Resonance Imaging, a magnetic scan that helps seeing inside the body in great detail) 7 to 14 days before joining the study * Take Extract of Ginkgo Biloba Leaves Tablets (240 mg per day) in addition to usual post-stroke treatment for 12…

Primary outcomes

  • Change in Montreal Cognitive Assessment (MoCA) Total Score
  • Change in Cognitive Function Using Trail Making Test (TMT) Parts A and B
  • Change in Cognitive Processing Speed Using Symbol Digit Modalities Test (SDMT)
  • Change in Verbal Fluency Performance Using Verbal Fluency Test (VFT)

History

  1. Primary completion expected

  2. Now active, not recruiting

    , from Recruiting to Active, not recruiting

  3. Last registry update

  4. Started

  5. Registered