No phaseCompletedHealthspan endpoint
Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome
- Sponsor
- Universidad de Burgos (Academic or other)
- Enrollment
- 32 enrolled
- Conditions
- Down Syndrome (DS); Supplementation
- Interventions
- Nutrition education; Supplement; Placebo
- Ages
- adults, older adults
- Registry
- NCT07213063
Full record on ClinicalTrials.gov
From the registry
Purpose: This study will test whether 8 weeks of creatine and HMB supplementation can improve muscle strength, body composition, balance, and overall health in people with Down syndrome. Participants will also receive nutrition tips during the study. Who can participate: People with Down syndrome who can perform basic physical tasks. Must provide consent from the participant and legal guardian. What participants will do: Take creatine (3 g/day) and HMB (3 g/day) or placebo for 8 weeks. Complete tests for muscle strength, balance, and cognitive function. Undergo body composition scans and give blood samples for health markers. Timing: All tests and blood samples are taken before and after each 8-week period. Importance: Results will help determine if creatine and HMB can safely improve strength, balance, and overall health in people with Down syndrome.
Primary outcomes
- Lean mass
History
Last registry update
Primary completion
Registered
Started