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No phaseCompletedHealthspan endpoint

Effectiveness of an Endurance Exercise Programme Preceded by Ischaemic Preconditioning in Older People

Effectiveness of an Endurance Exercise Programme Preceded by Ischaemic Preconditioning in Older People: a Randomised Clinical Trial

Sponsor
University of Valencia (Academic or other)
Enrollment
31 enrolled
Conditions
Older People
Interventions
IPC + Exercise protocol; Sham IPC + Exercise protocol
Ages
older adults
Registry
NCT05144815

Full record on ClinicalTrials.gov

From the registry

In recent decades, the proportion of people over 65 years of age is increasing rapidly, due to rising life expectancy and declining fertility rates. According to the World Health Organization, people in this age group will constitute 22% of the population by 2050, up from the current 12% (WHO, 2018). Therefore, improving quality of life (healthspan) and preventing disability has become a public health challenge (Olshansky, 2018). In this context, physical exercise has been shown to be able to prevent sarcopenia, functional decline, the presence of chronic diseases and even mortality in this group (Izquierdo et al., 2021; Lazarus, Lord, \& Harridge, 2019). A training method that could enhance the benefits of walking is ischaemic preconditioning (IPC), characterised by the application of brief periods of circulatory occlusion-reperfusion to a limb, minutes to hours prior to exercise. This type of intervention, initially used to delay/prevent cell damage in patients with myocardial infarction (Murry, Jennings, \& Reimer, 1986), has recently shown beneficial effects in young people to…

Primary outcomes

  • Cardiorespiratory fitness
  • Heart rate variability during walking

History

  1. Last registry update

  2. Study completion

  3. Primary completion

  4. Registered

  5. Started

Papers citing this trial