AgingResearch.NewsJoin free

Phase 1/2Recruiting

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

LCCC2032: The Effects of Short Chain Fatty Acid Supplementation on the Quality of Life and Treatment-related Toxicities in Subjects Receiving Abdominopelvic Radiotherapy: A Randomized Controlled Study

Sponsor
UNC Lineberger Comprehensive Cancer Center (Academic or other)
Enrollment
122 planned
Conditions
Toxicity; Radiation Toxicity
Interventions
Short Chain Fatty Acid; Tapioca Flour
Ages
adults, older adults
Registry
NCT04700527

Full record on ClinicalTrials.gov

From the registry

The purpose of this study is to assess and compare GI toxicity from RT between subjects who receive therapeutic SCFA and those who receive placebo, in hopes of identifying a safe, low-cost therapeutic to reduce GI toxicity from therapeutic or environmental radiation.

Primary outcomes

  • The rate and severity of patient reported and physician determined toxicities between subjects who receive therapeutic SCFA and those who receive placebo.

History

  1. Study completion expected

  2. Primary completion expected

  3. Last registry update

  4. Started

  5. Registered