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Biomarkers of Increased Free Living Sleep Time

Biomarkers and Altered Metabolic Pathways During Sleep Loss

Sponsor
University of Utah (Academic or other)
Enrollment
38 enrolled
Conditions
Sleep Deprivation; Insufficient Sleep Syndrome; Sleep Wake Disorders
Interventions
Increased sleep duration
Ages
adults
Registry
NCT04214184

Full record on ClinicalTrials.gov

From the registry

This protocol will increase sleep duration in participants who maintain less than 6 hours sleep per night, to target the recommended 7 hours of sleep per night. The focus of this study is determine how increasing nightly sleep duration in these individuals who maintain less than 6 hours sleep per night changes their plasma metabolome and insulin sensitivity. The primary outcome will examine changes in branched-chain amino acids and the secondary outcome will examine changes in insulin sensitivity. The investigators will also determine if changes in plasma metabolites can be used as a biomarker to discriminate between adequate versus insufficient sleep.

Primary outcomes

  • Metabolomics-branched chain amino acids change from baseline
  • Insulin Sensitivity change from baseline

History

  1. Last registry update

  2. Study completion

  3. Primary completion

  4. Registered

  5. Started

Papers citing this trial